POST 00989E : VVM USE AND FREEZE INDICATORS
Follow-up on Posts 00960E, 00962E, 00964E, 00970E, 00973E, 00975E and 00978E
11 October 2006
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This posting contains two short contributions. The first, originally in
French, is from Abdoulaye Djigo (mailto:[email protected]) from
Senegal if I am not mistaken. His suggestion would make sense, but I
believe that it is quite a technical problem with gas or kerosene
refrigerators. I gather that some experts will reply.
The second is from Sobhan Sarkar (mailto:[email protected]) from
India. Ãœmit Kartoglu (mailto:[email protected]) from WHO/HQ had discussed
this concept of freeze indicator in his contribution in the previous
posting (Post 00978E of 22 September).
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Contributions on VVMs and freeze indicators are very interesting. I wonder
if manufacturers could not introduce a special temperature probe to stop
the refrigerator from functioning, each time the temperature gets close to
the freezing point of vaccines. It would be like a supplementary
"thermostat" to ensure vaccine quality. Of course such a solution will mean
extra cost, but it will help to save vaccines.
Abdoulaye Oumar DJIGO
Expert-Consultant.
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TheT series and Hepatitis B vaccine is damaged by freezing. Freeze Watch is
one of the mean to detect such incidence. However, there is need to develop
VVM to detect such vials in which vaccine had frozen. Such VVM can be
imprinted on the label. In practice we have encountered damage to the
vaccine while transported in cold boxes or vaccine carriers due to direct
contact with solid frozen ice packs. This will help the end user to
identify damaged vaccine due to freezing.
Thus, such vaccine vials will have two VVMs one to indicate freezing the
other to indicate exposure to higher temparature.
This suggestion has been made by me on several occasions in the past.
Dr. Sobhan Sarkar NTA WHO/GoI
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