Article de revue
Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine
Oral vaccines, whether living or non-living, viral or bacterial, elicit diminished immune responses or have lower efficacy in developing countries than in developed countries. This research describe studies with a live oral cholera vaccine that include older children no longer deriving immune support from breast milk or maternal antibodies and that identify some of the factors accounting for the lower immunogenicity, as well as suggesting counter-measures that may enhance the effectiveness of oral immunization in developing countries.
Auteurs
Langues
- Anglais
Année de publication
2010
Journal
BMC Biology
Volume
129
Type
Article de revue
Catégories
- Vaccins et dispositifs d'administration
Maladies
- Polio
Pays
- Inde
- Indonésie
- Thaïlande
Mots-clés
- Introduction de nouveaux vaccins
Régions de l'OMS
- Région de l'Asie du Sud-Est