Article de revue
Prospects for control of emerging infectious diseases with plasmid DNA vaccines
Experiments almost 20 years ago demonstrated that injections of a sequence of DNA encoding part of a pathogen could stimulate immunity. It was soon realized that \"DNA vaccination\" had numerous potential advantages over conventional vaccine approaches including inherent safety and a more rapid production time. These and other attributes make DNA vaccines ideal for development against emerging pathogens. Recent advances in optimizing various aspects of DNA vaccination have accelerated this approach from concept to reality in contemporary human trials. Although not yet licensed for human use, several DNA vaccines have now been approved for animal health indications. The rapid manufacturing capabilities of DNA vaccines may be particularly important for emerging infectious diseases including the current novel H1N1 Influenza A pandemic, where pre-existing immunity is limited. Because of recent advances in DNA vaccination, this approach has the potential to be a powerful new weapon in protecting against emerging and potentially pandemic human pathogens.
Auteurs
Langues
- Anglais
Année de publication
2009
Journal
Journal of Immune Based Therapies and Vaccines
Volume
7
Type
Article de revue
Catégories
- Prestation de services
Maladies
- HIB
Mots-clés
- Introduction de nouveaux vaccins