Article de revue
The economic value of a visceral leishmaniasis vaccine in Bihar state, India
Visceral leishmaniasis (VL) is responsible for substantial morbidity and mortality and current available treatments have many limitations. The ability of VL infection to generate life-long immunity offers promise for the development of a VL vaccine. A VL vaccine candidate has recently completed phase I clinical trials. We constructed a computer simulation model to determine the potential economic value of a VL vaccine in the endemic region of Bihar state, India. Results found a potential vaccine to be cost-effective (and in many cases economically dominant, i.e., saving costs and providing health benefits) throughout a wide range of vaccination costs and vaccine efficacies, and VL risks. Overall, our study strongly supports the continued development of a VL vaccine.
Auteurs
Langues
- Anglais
Année de publication
2012
Journal
Am J Trop Med Hyg
Volume
3
Type
Article de revue
Catégories
- Vaccins et dispositifs d'administration
Pays
- Inde
Mots-clés
- Introduction de nouveaux vaccins
Régions de l'OMS
- Région de l'Asie du Sud-Est