Identifying optimal vaccination strategies for serogroup A Neisseria Meningitidis Conjugate vaccine in the African meningitis belt

The optimal long-term vaccination strategies to provide population-level protection against serogroup A Neisseria meningitidis (MenA) are unknown. We developed an age-structured mathematical model of MenA transmission, colonization, and disease in the African meningitis belt, and used this model to explore the impact of various vaccination strategies.